1,2-ethanedisulfonic acid 1,2-ethanedisulfonic acid
structural formula
| business number | 030g |
|---|---|
| molecular formula | c2h6o6s2 |
| molecular weight | 190.2 |
| label |
ethane disulfonic acid, 1,2-ethanedisulfonic acid hydrate, 1,2-ethanedisulfonic acid dihydrate, aliphatic compounds |
numbering system
cas number:110-04-3
mdl number:mfcd00069901
einecs number:203-732-0
rtecs number:none
brn number:none
pubchem id:none
physical property data
1. properties: needle-like crystals
2. solubility: soluble in ethanol and ether.
toxicological data
none yet
ecological data
none yet
molecular structure data
1. molar refractive index: 32.00
2. molar volume (cm3/mol): 198.6
3. isotonic specific volume (90.2k ): 311.5
4. surface tension (dyne/cm): 99.5
5. polarizability (10-24cm3): 12.68
compute chemical data
1. hydrophobic parameter calculation reference value (xlogp): -2.2
2. number of hydrogen bond donors: 0
3. number of hydrogen bond acceptors: 6
p>
4. number of rotatable chemical bonds: 1
5. number of tautomers:
6. topological molecular polar surface area (tpsa): 114
p>
7. number of heavy atoms: 10
8. surface charge: -2
9. complexity: 212
10. isotopic atoms quantity: 0
11. determine the number of atomic stereocenters: 0
12. uncertain number of atomic stereocenters: 0
13. determine the chemical bond structure number of stereocenters: 0
14. number of uncertain chemical bond stereocenters: 0
15. number of covalent bond units: 1
properties and stability
it is corrosive and irritating. skin contact may cause allergic reactions. operators should wear protective equipment.
storage method
synthesis method
1,2-dichloroethane undergoes a displacement reaction with sodium sulfite to produce ethane disulfonic acid disodium salt. dissolve the sodium salt in water, pass it through an exchange column equipped with 001×7 type strongly acidic styrene-based cation exchange resin (732#) at a speed of 2.5~3kg/h, and collect the exchange liquid in sections, with ph=3~1 part containing more than 90% ethane disulfonic acid, it is concentrated under reduced pressure to remove water and becomes syrupy. dry at 100℃ to get the finished product.
purpose
pharmaceutical intermediates. used in the production of non-narcotic cough medicine cemifene.
