vinblastine sulfate
structural formula
| business number | 03w8 |
|---|---|
| molecular formula | c46h60n4o13s |
| molecular weight | 909.05 |
| label |
vincaleukoblastine sulfate salt |
numbering system
cas number:143-67-9
mdl number:mfcd00082457
einecs number:205-606-0
rtecs number:yy8400000
brn number:3659812
pubchem number:24278771
physical property data
1. physical property data:
1. melting point (ºc): 267ºc
2. specific optical rotation (º): -21.7 º
toxicological data
2. �physics data:
1, acute toxicity: rat oral ld50: 305 mg/kg;
rat abdominal cavity ld50: 1 mg/kg;
rat subcutaneous ld50: 355 mg/kg;
rat veinld50：37 mg/kg;
mice orallyld50: 423 mg/kg;
mouse abdominal cavity ld50: 2700 ug/kg；
mouse subcutaneous ld50: 324 mg/kg.
ecological data
3. ecological data:
other harmful effect: this substance may be harmful to the environment, and special attention should be paid to water bodies.
molecular structure data
none
compute chemical data
4. calculated chemical data:
1. hydrogen bonding number of donors: 5
2. hydrogen bonding number of receptors: 16
3. rotatable number of chemical bonds: 10
4. topological molecules polar surface area (tpsa）：229
5. heavy atoms quantity: 64
6. surface charge ：0
7. complexity ：1780
8. isotope atomic number:0
9. determine the number of atomic stereocenters:9
10. uncertain number of atomic stereocenters:0
11. determine the number of stereocenters of chemical bonds:0
12. uncertain number of chemical bond stereocenters:0
13. number of covalent bond units: 2
properties and stability
stable under normal temperature and pressure.
storage method
save at 2-8ºc.
synthesis method
none
purpose
1.anti-tumor drugs, used to treat hodgkin’s disease and chorioepithelial carcinoma, and also have certain effects on lymphosarcoma, acute leukemia, breast cancer, etc..
2.anti-tumor drug for malignant lymphoma
an’; mso-bidi-font-family: 宋体”>
1.anti-tumor drugs, used to treat hodgkin’s disease and chorioepithelial carcinoma, and also have certain effects on lymphosarcoma, acute leukemia, breast cancer, etc..
2.anti-tumor drug for malignant lymphoma
