tolbutamide tolbutamide
structural formula
| business number | 01dj |
|---|---|
| molecular formula | c12h18n2o3s |
| molecular weight | 270.35 |
| label |
1-n-butyl-3-(4-methylsulfonyl)urea, 1-butyl-3-(4-methylphenylsulfonyl)urea |
numbering system
cas number:64-77-7
mdl number:mfcd00027169
einecs number:200-594-3
rtecs number:ys4550000
brn number:1984428
pubchem number:24277742
physical property data
1. character:white crystalline powder. odorless and tasteless
2. density (g/ml,25/4℃): unsure
3. relative vapor density (g/ml,air=1): unsure
4. melting point (ºc):128 -130
5. boiling point (ºc,normal pressure): uncertain
6. boiling point (ºc, 5.2kpa): unsure
7. refractive index:not sure
8. flash point (ºc): unsure
9. specific optical rotation (º): unsure
10. autoignition point or ignition temperature (ºc): unsure
11. vapor pressure (kpa,25ºc): unsure
12. <span style="font-size: 9pt; font-family: 宋体; mso-ascii-font-family: arial; mso-hansi-font-fa): 583.5
4. surface tension (dyne/cm):42.7
5. polarizability（10-24cm3): 28.05
compute chemical data
1. reference value for hydrophobic parameter calculation (xlogp): none
2. number of hydrogen bond donors: 2
3. number of hydrogen bond acceptors: 3
4. number of rotatable chemical bonds: 5
5. number of tautomers: 3
6. topological molecule polar surface area 83.6
7. number of heavy atoms: 18
8. surface charge: 0
9. complexity: 354
10. number of isotope atoms: 0
11. determine the number of atomic stereocenters: 0
12. uncertain number of atomic stereocenters: 0
13. determine the number of chemical bond stereocenters: 0
14. number of uncertain chemical bond stereocenters: 0
15. number of covalent bond units: 1
properties and stability
none yet
storage method
this product should be sealed in 0℃save the following in a dry place and away from light.
synthesis method
prepared from the condensation of butyl isocyanate and p-toluenesulfonamide, or from the condensation of n-butylamine hydrochloride and toluenesulfonylurea become.
purpose
a hypoglycemic drug, suitable for adult patients with stable mild to moderate diabetes.
ng=en-us style=”font-size: 9pt; font-family: arial; mso-font-kerning: 0pt”>
purpose
a hypoglycemic drug, suitable for adult patients with stable mild to moderate diabetes.
