5-nitro-2-furaldehyde semicarbazone 5-nitro-2-furaldehyde semicarbazone
structural formula
| business number | 01aq |
|---|---|
| molecular formula | c6h6n4o4 |
| molecular weight | 198.14 |
| label |
nitrofurazone, furacin, nfz, nitrofurazone |
numbering system
cas number:59-87-0
mdl number:mfcd00003225
einecs number:200-443-1
rtecs number:lt7700000
brn number:86403
pubchem number:24886543
physical property data
1. characteristics: yellow crystalline powder.
2. density (g/ml,25/4℃)： undetermined
3. relative steam density (g/ml,air=1) : undetermined
4. melting point (ºc):236 -240℃ (decomposition).
5. boiling point (ºc,normal pressure): undetermined
6. boiling point (ºc,5.2kpa): undetermined
7. refractive index: undetermined
8. flash point (ºc): undetermined
9. specific optical rotation (º): undetermined
10. autoignition point or ignition temperature (ºc): undetermined
11. vapor pressure (kpa,25ºc): undetermined
12. 43.56
2. molar volume (m3/mol）：116.0
3. isotonic specific volume (90.2k):348.1
4. surface tension (dyne/cm):81.0
5. polarizability(10-24cm3):17.27
compute chemical data
1. reference value for hydrophobic parameter calculation (xlogp): none
2. number of hydrogen bond donors: 2
3. number of hydrogen bond acceptors: 5
4. number of rotatable chemical bonds: 2
5. number of tautomers: 3
6. topological molecule polar surface area 126
7. number of heavy atoms: 14
8. surface charge: 0
9. complexity: 261
10. number of isotope atoms: 0
11. determine the number of atomic stereocenters: 0
12. uncertain number of atomic stereocenters: 0
13. determine the number of chemical bond stereocenters: 1
14. number of uncertain chemical bond stereocenters: 0
15. number of covalent bond units: 1
properties and stability
none yet
storage method
prepared from furfural through nitration, esterification and hydrolysis5-nitrofurfural, and then condensed with amino hydrochloride to obtain nitrofurazone.
synthesis method
prepared from furfural through nitration, esterification and hydrolysis5-nitrofurfural, and then condensed with amino hydrochloride to obtain nitrofurazone.
purpose
this product is a nitrofuran antibacterial drug. this class of drugs also includes furazolidone and nitrofurantoin. nitrofuracillin is highly toxic when taken orally and is used for local or surface disinfection in surgery.
: 0cm 0cm 0pt; text-align: left; mso-pagination: wi-orphan; mso-margin-top-alt: auto; mso-margin-bottom-alt: auto” align=left>by furfural is prepared through nitration, esterification and hydrolysis5- span>nitrofurfural is condensed with the amino acid hydrochloride to obtain nitrofuracillin.
synthesis method
prepared from furfural through nitration, esterification and hydrolysis5-nitrofurfural, and then condensed with amino hydrochloride to obtain nitrofurazone.
purpose
this product is a nitrofuran antibacterial drug. this class of drugs also includes furazolidone and nitrofurantoin. nitrofuracillin is highly toxic when taken orally and is used for local or surface disinfection in surgery.